CD36 - significado y definición. Qué es CD36
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Qué (quién) es CD36 - definición


CD36         
CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene. The CD36 antigen is an integral membrane protein found on the surface of many cell types in vertebrate animals.
CD36 antigen         
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CD36 antigen is a transmembrane, highly glycosylated, glycoprotein expressed by monocytes, macrophages, platelets, microvascular endothelial cells and adipose tissues. CD36 recognises oxidized low density lipoprotein, long chain fatty acids, anionic phospholipids, collagen types I, IV and V, thrombospondin and Plasmodium falciparum infected erythrocytes.
Ejemplos de uso de CD36
1. To see whether CD36 might be the tongue‘s fat detector, Besnard and his colleagues studied rats and mice that were either normal or had the gene for CD36 "knocked out," inactivating the protein.
2. Again, the same was not true of mice lacking CD36 activity.
3. They found that while the genetically normal animals naturally opted for fattier fare when given the choice, the CD36–deficient mice had no such preference.
4. Though the body‘s regulation of fat intake is complex, these findings point to the importance of CD36 receptors on the tongue, Besnard told Reuters Health.
5. The receptor, a protein called CD36, is already known to exist in many tissues and is involved in fat storage, among other jobs; it is also goes by the name of fatty acid transporter, or FAT.